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Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein
The yeast splicing factor Cwc2 contacts several catalytically important RNA elements in the active spliceosome, suggesting that Cwc2 is involved in determining their spatial arrangement at the spliceosome's catalytic centre. We have determined the crystal structure of the Cwc2 functional core,...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343462/ https://ncbi.nlm.nih.gov/pubmed/22407296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.58 |
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