Chemical synthesis of a biologically active natural tRNA with its minor bases.

The complete chemical synthesis of an E. coli tRNA(Ala) with its specific minor nucleosides, dihydrouridine, ribothymidine and pseudouridine, is reported. The method makes use of protected 2'-O-tertiobutyldimethylsilyl-ribonucleoside-3'-O-(2-cyanoethyl-N- ethyl-N- methyl)phosphoramidites. The exocyc...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Gasparutto, D, Livache, T, Bazin, H, Duplaa, A M, Guy, A, Khorlin, A, Molko, D, Roget, A, Téoule, R
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 1992
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5159
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