Chemical synthesis of a biologically active natural tRNA with its minor bases.

The complete chemical synthesis of an E. coli tRNA(Ala) with its specific minor nucleosides, dihydrouridine, ribothymidine and pseudouridine, is reported. The method makes use of protected 2'-O-tertiobutyldimethylsilyl-ribonucleoside-3'-O-(2-cyanoethyl-N- ethyl-N- methyl)phosphoramidites. The exocyc...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Gasparutto, D, Livache, T, Bazin, H, Duplaa, A M, Guy, A, Khorlin, A, Molko, D, Roget, A, Téoule, R
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1992
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5159
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