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Synthesis of DNA fragments containing 5,6-dihydrothymine, a major product of thymine gamma radiolysis.
5,6-Dihydrothymine is one of the most important products of base damage by gamma irradiation of DNA in anoxic conditions. This modified base is unstable in the deprotection conditions used for classical synthesis of oligonucleotides. For its incorporation in synthetic DNA fragments, a new set of ami...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1988
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334629/ https://ncbi.nlm.nih.gov/pubmed/3340528 |
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