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Synthesis of DNA fragments containing 5,6-dihydrothymine, a major product of thymine gamma radiolysis.

5,6-Dihydrothymine is one of the most important products of base damage by gamma irradiation of DNA in anoxic conditions. This modified base is unstable in the deprotection conditions used for classical synthesis of oligonucleotides. For its incorporation in synthetic DNA fragments, a new set of ami...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schulhof, J C, Molko, D, Teoule, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC334629/
https://ncbi.nlm.nih.gov/pubmed/3340528
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