Chemical synthesis of a biologically active natural tRNA with its minor bases.

The complete chemical synthesis of an E. coli tRNA(Ala) with its specific minor nucleosides, dihydrouridine, ribothymidine and pseudouridine, is reported. The method makes use of protected 2'-O-tertiobutyldimethylsilyl-ribonucleoside-3'-O-(2-cyanoethyl-N- ethyl-N- methyl)phosphoramidites. The exocyc...

Полное описание

Библиографические подробности

Опубликовано в::	Nucleic Acids Res
Главные авторы:	Gasparutto, D, Livache, T, Bazin, H, Duplaa, A M, Guy, A, Khorlin, A, Molko, D, Roget, A, Téoule, R
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 1992
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5159
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