Chemical synthesis of a biologically active natural tRNA with its minor bases.
The complete chemical synthesis of an E. coli tRNA(Ala) with its specific minor nucleosides, dihydrouridine, ribothymidine and pseudouridine, is reported. The method makes use of protected 2'-O-tertiobutyldimethylsilyl-ribonucleoside-3'-O-(2-cyanoethyl-N- ethyl-N- methyl)phosphoramidites. The exocyc...
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| I publikationen: | Nucleic Acids Res |
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| Huvudupphov: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Oxford University Press
1992
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| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5159 |
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