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Structural basis for negative cooperativity within agonist-bound TR:RXR heterodimers
Thyroid hormones such as 3,3′,5 triiodo-l-thyronine (T3) control numerous aspects of mammalian development and metabolism. The actions of such hormones are mediated by specific thyroid hormone receptors (TRs). TR belongs to the nuclear receptor family of modular transcription factors that binds to s...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341017/ https://ncbi.nlm.nih.gov/pubmed/22474364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119852109 |
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