Modification at the Lipophilic Domain of RXR Agonists Differentially Influences Activation of RXR Heterodimers

[Image: see text] RXR permissive heterodimers are reported to be activated differently depending upon the chemical structure of RXR agonists, but the relationship of agonist structure to differential heterodimer activation has not been explored in detail. In this study, we performed systematic conve...

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Главные авторы: Ohsawa, Fuminori, Morishita, Ken-ichi, Yamada, Shoya, Makishima, Makoto, Kakuta, Hiroki
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2010
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007838/
https://ncbi.nlm.nih.gov/pubmed/24900241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100184k
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