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The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission
Assessing the physical connections and allosteric communications in multi-domain nuclear receptor (NR) polypeptides has remained challenging, with few crystal structures available to show their overall structural organizations. Here we report the quaternary architecture of multi-domain retinoic acid...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636793/ https://ncbi.nlm.nih.gov/pubmed/29021580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00981-y |
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