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Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer
The MED1 subunit of the Mediator complex is an essential coactivator of nuclear receptor-mediated transcriptional activation. While structural requirements for ligand-dependent binding of classical coactivator motifs of MED1 to numerous nuclear receptor ligand-binding domains have been fully elucida...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641746/ https://ncbi.nlm.nih.gov/pubmed/32990725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa775 |
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