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Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA
Transcription regulation by steroid hormones and other metabolites is mediated by nuclear receptors (NRs) such as the vitamin D and retinoid X receptors (VDR and RXR). Here, we present the cryo electron microscopy (cryo-EM) structure of the heterodimeric complex of the liganded human RXR and VDR bou...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261568/ https://ncbi.nlm.nih.gov/pubmed/22179700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.445 |
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