MDM2 Promoter SNP344T>A (rs1196333) Status Does Not Affect Cancer Risk

The MDM2 proto-oncogene plays a key role in central cellular processes like growth control and apoptosis, and the gene locus is frequently amplified in sarcomas. Two polymorphisms located in the MDM2 promoter P2 have been shown to affect cancer risk. One of these polymorphisms (SNP309T>G; rs22797...

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Main Authors: Knappskog, Stian, Gansmo, Liv B., Romundstad, Pål, Bjørnslett, Merete, Trovik, Jone, Sommerfelt-Pettersen, Jan, Løkkevik, Erik, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Devilee, Peter, Salvesen, Helga B., Dørum, Anne, Hveem, Kristian, Vatten, Lars, Lønning, Per E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340411/
https://ncbi.nlm.nih.gov/pubmed/22558411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036263
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