The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer

The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in several cancer forms. Recently, a single nucleotide polymorphism (SNP) in the...

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Detalhes bibliográficos
Publicado no:Tumour Biol
Main Authors: Gansmo, Liv B., Bjørnslett, Merete, Halle, Mari Kyllesø, Salvesen, Helga B., Dørum, Anne, Birkeland, Einar, Hveem, Kristian, Romundstad, Pål, Vatten, Lars, Lønning, Per Eystein, Knappskog, Stian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999457/
https://ncbi.nlm.nih.gov/pubmed/26867771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-4940-2
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