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MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

BACKGROUND: The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact of MDM2...

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Pubblicato in:BMC Cancer
Autori principali: Gansmo, Liv B., Bjørnslett, Merete, Halle, Mari Kyllesø, Salvesen, Helga B., Romundstad, Pål, Hveem, Kristian, Vatten, Lars, Dørum, Anne, Lønning, Per E., Knappskog, Stian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291962/
https://ncbi.nlm.nih.gov/pubmed/28158999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3094-y
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