Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.

We have used alpha-oligomers as antisense oligonucleotides complementary to three different sequences of the rabbit beta-globin mRNA: a region adjacent to the cap site, a region spanning the AUG initiation codon or a sequence in the coding region. These alpha-oligonucleotides were synthesized either...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Boiziau, C, Kurfurst, R, Cazenave, C, Roig, V, Thuong, N T, Toulmé, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1991
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.5.1113
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