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Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.

We have used alpha-oligomers as antisense oligonucleotides complementary to three different sequences of the rabbit beta-globin mRNA: a region adjacent to the cap site, a region spanning the AUG initiation codon or a sequence in the coding region. These alpha-oligonucleotides were synthesized either...

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Bibliografski detalji
Glavni autori: Boiziau, C, Kurfurst, R, Cazenave, C, Roig, V, Thuong, N T, Toulmé, J J
Format: Artigo
Jezik:Inglês
Izdano: 1991
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC333789/
https://ncbi.nlm.nih.gov/pubmed/1850511
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