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Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.
We have used alpha-oligomers as antisense oligonucleotides complementary to three different sequences of the rabbit beta-globin mRNA: a region adjacent to the cap site, a region spanning the AUG initiation codon or a sequence in the coding region. These alpha-oligonucleotides were synthesized either...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1991
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333789/ https://ncbi.nlm.nih.gov/pubmed/1850511 |
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