Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.
We have used alpha-oligomers as antisense oligonucleotides complementary to three different sequences of the rabbit beta-globin mRNA: a region adjacent to the cap site, a region spanning the AUG initiation codon or a sequence in the coding region. These alpha-oligonucleotides were synthesized either...
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| 發表在: | Nucleic Acids Res |
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| Principais autores: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1991
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| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.5.1113 |
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