COMPOUND HETEROZYGOUS LOSS OF Ext1 AND Ext2 IS SUFFICIENT FOR FORMATION OF MULTIPLE EXOSTOSES IN POSTNATAL MOUSE LONG BONES IN MICE

Ítems similars

• Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses
  per: Huegel, Julianne, et al.
  Publicat: (2013)
• Mice deficient in Ext2 lack heparan sulfate and develop exostoses
  per: Stickens, Dominique, et al.
  Publicat: (2005)
• Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine
  per: Mundy, Christina, et al.
  Publicat: (2010)
• Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice()
  per: Sgariglia, Federica, et al.
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• Assessing the general population frequency of rare coding variants in the EXT1 and EXT2 genes previously implicated in Hereditary Multiple Exostoses
  per: Cousminer, Diana L., et al.
  Publicat: (2016)