Učitavanje...
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine
Heparan sulfate proteoglycans (HSPGs) regulate a number of major developmental processes, but their roles in synovial joint formation remain unknown. Here we created conditional mouse embryo mutants lacking Ext1 in developing joints by mating Ext1(f/f) and Gdf5-Cre mice. Ext1 encodes a subunit of th...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039051/ https://ncbi.nlm.nih.gov/pubmed/21185280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.022 |
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