Lanean...

Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine

Heparan sulfate proteoglycans (HSPGs) regulate a number of major developmental processes, but their roles in synovial joint formation remain unknown. Here we created conditional mouse embryo mutants lacking Ext1 in developing joints by mating Ext1(f/f) and Gdf5-Cre mice. Ext1 encodes a subunit of th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mundy, Christina, Yasuda, Tadashi, Kinumatsu, Takashi, Yamaguchi, Yu, Iwamoto, Masahiro, Enomoto-Iwamoto, Motomi, Koyama, Eiki, Pacifici, Maurizio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039051/
https://ncbi.nlm.nih.gov/pubmed/21185280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.022
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!