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Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses

During limb skeletogenesis the cartilaginous long bone anlagen and their growth plates become delimited by perichondrium with which they interact functionally. Yet, little is known about how, despite being so intimately associated with cartilage, perichondrium acquires and maintains its distinct phe...

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Detalhes bibliográficos
Main Authors: Huegel, Julianne, Mundy, Christina, Sgariglia, Federica, Nygren, Patrik, Billings, Paul C., Yamaguchi, Yu, Koyama, Eiki, Pacifici, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733121/
https://ncbi.nlm.nih.gov/pubmed/23458899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.02.008
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