Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice()

Long bones are integral components of the limb skeleton. Recent studies have indicated that embryonic long bone development is altered by mutations in Ext genes and consequent heparan sulfate (HS) deficiency, possibly due to changes in activity and distribution of HS-binding/growth plate-associated...

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Main Authors: Sgariglia, Federica, Candela, Maria Elena, Huegel, Julianne, Jacenko, Olena, Koyama, Eiki, Yamaguchi, Yu, Pacifici, Maurizio, Enomoto-Iwamoto, Motomi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107462/
https://ncbi.nlm.nih.gov/pubmed/23958822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.08.012
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