Llwytho...

Identification and Characterization of Small Molecule Antagonists of pRb Inactivation by Viral Oncoproteins

The retinoblastoma protein pRb is essential for regulating many cellular activities through its binding and inhibition of E2F transcription activators, and pRb inactivation leads to many cancers. pRb activity can be perturbed by viral oncoproteins including human papillomavirus (HPV) that share an L...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fera, Daniela, Schultz, David C., Hodawadekar, Santosh, Reichman, Melvin, Donover, Preston Scott, Melvin, Jason, Troutman, Scott, Kissil, Joseph, Huryn, Donna M., Marmorstein, Ronen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334872/
https://ncbi.nlm.nih.gov/pubmed/22520758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.03.007
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