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Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
BACKGROUND: Structural rearrangements form a major class of somatic variation in cancer genomes. Local chromosome shattering, termed chromothripsis, is a mechanism proposed to be the cause of clustered chromosomal rearrangements and was recently described to occur in a small percentage of tumors. Th...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3333773/ https://ncbi.nlm.nih.gov/pubmed/22014273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-10-r103 |
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