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Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells
BACKGROUND: Germline chromothripsis causes complex genomic rearrangements that are likely to affect multiple genes and their regulatory contexts. The contribution of individual rearrangements and affected genes to the phenotypes of patients with complex germline genomic rearrangements is generally u...
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| Publicat a: | Genome Med |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270341/ https://ncbi.nlm.nih.gov/pubmed/28126037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0399-z |
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