Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

Cancer cells often harbor chromosomes in abnormal numbers and with aberrant structure. The consequences of these chromosomal aberrations are difficult to study in cancer, and therefore several model systems have been developed in recent years. We show that human cells with extra chromosome engineere...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Kneissig, Maja, Keuper, Kristina, de Pagter, Mirjam S, van Roosmalen, Markus J, Martin, Jana, Otto, Hannah, Passerini, Verena, Campos Sparr, Aline, Renkens, Ivo, Kropveld, Fenna, Vasudevan, Anand, Sheltzer, Jason M, Kloosterman, Wigard P, Storchova, Zuzana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2019
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910827/
https://ncbi.nlm.nih.gov/pubmed/31778112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50292
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller