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Too much to handle — how gaining chromosomes destabilizes the genome

Most eukaryotic organisms are diploid, with 2 chromosome sets in their nuclei. Whole chromosomal aneuploidy, a deviation from multiples of the haploid chromosome number, arises from chromosome segregation errors and often has detrimental consequences for cells. In humans, numerical aneuploidy severe...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Passerini, Verena, Storchová, Zuzana
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105935/
https://ncbi.nlm.nih.gov/pubmed/27636196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1231285
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