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Genomic and transcriptomic plasticity in treatment-naïve ovarian cancer
Intra-tumor heterogeneity is a hallmark of many cancers and may lead to therapy resistance or interfere with personalized treatment strategies. Here, we combined topographic mapping of somatic breakpoints and transcriptional profiling to probe intra-tumor heterogeneity of treatment-naïve stage IIIC/...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912411/ https://ncbi.nlm.nih.gov/pubmed/24221193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161026.113 |
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