Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

Microsomal triglyceride transfer protein (Mtp) inhibitors represent a novel therapeutic approach to lower circulating LDL cholesterol, although therapeutic development has been hindered by the observed increase in hepatic triglycerides and liver steatosis following treatment. Here, we used small int...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tep, Samnang, Mihaila, Radu, Freeman, Alexander, Pickering, Victoria, Huynh, Felicia, Tadin-Strapps, Marija, Stracks, Allison, Hubbard, Brian, Caldwell, Jeremy, Flanagan, W. Michael, Kuklin, Nelly A., Ason, Brandon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329385/
https://ncbi.nlm.nih.gov/pubmed/22355095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021063
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