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CD98 siRNA-loaded nanoparticles decrease hepatic steatosis in mice

Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid hepatic accumulation. Here, we investigated whether a reduction of CD98 expression mediated by CD98 siRNA-loaded nanoparticles (NPs) could attenuate liver disease markers in a mouse model of NAFLD. NPs were generated using...

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Bibliografski detalji
Izdano u:Dig Liver Dis
Glavni autori: Canup, Brandon S.B., Song, Heliang, Le Ngo, Vu, Meng, Xiangxiao, Denning, Timothy L., Garg, Pallavi, Laroui, Hamed
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475075/
https://ncbi.nlm.nih.gov/pubmed/27939923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dld.2016.11.008
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