Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

Microsomal triglyceride transfer protein (Mtp) inhibitors represent a novel therapeutic approach to lower circulating LDL cholesterol, although therapeutic development has been hindered by the observed increase in hepatic triglycerides and liver steatosis following treatment. Here, we used small int...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tep, Samnang, Mihaila, Radu, Freeman, Alexander, Pickering, Victoria, Huynh, Felicia, Tadin-Strapps, Marija, Stracks, Allison, Hubbard, Brian, Caldwell, Jeremy, Flanagan, W. Michael, Kuklin, Nelly A., Ason, Brandon
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329385/
https://ncbi.nlm.nih.gov/pubmed/22355095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021063
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares