Nalaganje...

Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β

To understand how virulent mycobacteria subvert host immunity and establish disease, we examined the differential response of mice to infection with various human outbreak Mycobacterium tuberculosis clinical isolates. One clinical isolate, HN878, was found to be hypervirulent, as demonstrated by unu...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Manca, Claudia, Tsenova, Liana, Bergtold, Amy, Freeman, Sherry, Tovey, Michael, Musser, James M., Barry, Clifton E., Freedman, Victoria H., Kaplan, Gilla
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC33285/
https://ncbi.nlm.nih.gov/pubmed/11320211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091096998
Oznake: Označite
Brez oznak, prvi označite!