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Genetic Loss of Insulin Receptors Worsens Cardiac Efficiency in Diabetes
AIMS: To determine the contribution of insulin signaling versus systemic metabolism to metabolic and mitochondrial alterations in type 1 diabetic hearts and test the hypothesis that antecedent mitochondrial dysfunction contributes to impaired cardiac efficiency (CE) in diabetes. METHODS AND RESULTS:...
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327790/ https://ncbi.nlm.nih.gov/pubmed/22342406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.02.001 |
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