Hepatitis C Viral Evolution in Genotype 1 Treatment-Naïve and Treatment-Experienced Patients Receiving Telaprevir-Based Therapy in Clinical Trials

BACKGROUND: In patients with genotype 1 chronic hepatitis C infection, telaprevir (TVR) in combination with peginterferon and ribavirin (PR) significantly increased sustained virologic response (SVR) rates compared with PR alone. However, genotypic changes could be observed in TVR-treated patients w...

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Autores principales: Kieffer, Tara L., De Meyer, Sandra, Bartels, Doug J., Sullivan, James C., Zhang, Eileen Z., Tigges, Ann, Dierynck, Inge, Spanks, Joan, Dorrian, Jennifer, Jiang, Min, Adiwijaya, Bambang, Ghys, Anne, Beumont, Maria, Kauffman, Robert S., Adda, Nathalie, Jacobson, Ira M., Sherman, Kenneth E., Zeuzem, Stefan, Kwong, Ann D., Picchio, Gaston
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325239/
https://ncbi.nlm.nih.gov/pubmed/22511937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034372
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