Modeling Viral Evolutionary Dynamics after Telaprevir-Based Treatment

For patients infected with hepatitis C virus (HCV), the combination of the direct-acting antiviral agent telaprevir, pegylated-interferon alfa (Peg-IFN), and ribavirin (RBV) significantly increases the chances of sustained virologic response (SVR) over treatment with Peg-IFN and RBV alone. If patien...

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Autors principals: Haseltine, Eric L., De Meyer, Sandra, Dierynck, Inge, Bartels, Doug J., Ghys, Anne, Davis, Andrew, Zhang, Eileen Z., Tigges, Ann M., Spanks, Joan, Picchio, Gaston, Kieffer, Tara L., Sullivan, James C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138032/
https://ncbi.nlm.nih.gov/pubmed/25101970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003772
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