Hepatitis C Viral Evolution in Genotype 1 Treatment-Naïve and Treatment-Experienced Patients Receiving Telaprevir-Based Therapy in Clinical Trials

BACKGROUND: In patients with genotype 1 chronic hepatitis C infection, telaprevir (TVR) in combination with peginterferon and ribavirin (PR) significantly increased sustained virologic response (SVR) rates compared with PR alone. However, genotypic changes could be observed in TVR-treated patients w...

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Main Authors: Kieffer, Tara L., De Meyer, Sandra, Bartels, Doug J., Sullivan, James C., Zhang, Eileen Z., Tigges, Ann, Dierynck, Inge, Spanks, Joan, Dorrian, Jennifer, Jiang, Min, Adiwijaya, Bambang, Ghys, Anne, Beumont, Maria, Kauffman, Robert S., Adda, Nathalie, Jacobson, Ira M., Sherman, Kenneth E., Zeuzem, Stefan, Kwong, Ann D., Picchio, Gaston
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325239/
https://ncbi.nlm.nih.gov/pubmed/22511937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034372
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