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Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro
Human telomeres consist of multiple tandem hexameric repeats, each containing a guanine triplet. Guanosine-rich clusters are highly susceptible to oxidative base damage, necessitating base excision repair (BER). Previous demonstration of enhanced strand displacement synthesis by the BER component DN...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323798/ https://ncbi.nlm.nih.gov/pubmed/22336916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.5.19483 |
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