Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex

Base excision repair, a major repair pathway in mammalian cells, is responsible for correcting DNA base damage and maintaining genomic integrity. Recent reports show that the Rad9-Rad1-Hus1 complex (9-1-1) stimulates enzymes proposed to perform a long patch-base excision repair sub-pathway (LP-BER),...

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Detalhes bibliográficos
Main Authors: Balakrishnan, Lata, Brandt, Patrick D., Lindsey-Boltz, Laura A., Sancar, Aziz, Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685697/
https://ncbi.nlm.nih.gov/pubmed/19329425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000505
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