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Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair

Ribonucleotides are incorporated into the genome during DNA replication. The enzyme RNase H2 plays a critical role in targeting the removal of these ribonucleotides from DNA, and defects in RNase H2 activity are associated with both genomic instability and the human autoimmune/inflammatory disorder...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lindsey-Boltz, Laura A., Kemp, Michael G., Hu, Jinchuan, Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705967/
https://ncbi.nlm.nih.gov/pubmed/26491008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695254
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