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Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair
Ribonucleotides are incorporated into the genome during DNA replication. The enzyme RNase H2 plays a critical role in targeting the removal of these ribonucleotides from DNA, and defects in RNase H2 activity are associated with both genomic instability and the human autoimmune/inflammatory disorder...
Guardat en:
Publicat a: | J Biol Chem |
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Autors principals: | , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Biochemistry and Molecular Biology
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705967/ https://ncbi.nlm.nih.gov/pubmed/26491008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695254 |
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