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Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System

DNA repair and DNA damage checkpoints work in concert to help maintain genomic integrity. In vivo data suggest that these two global responses to DNA damage are coupled. It has been proposed that the canonical 30 nucleotide single-stranded DNA gap generated by nucleotide excision repair is the signa...

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Main Authors: Lindsey-Boltz, Laura A., Kemp, Michael G., Reardon, Joyce T., DeRocco, Vanessa, Iyer, Ravi R., Modrich, Paul, Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931066/
https://ncbi.nlm.nih.gov/pubmed/24403078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.542787
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