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DNA base excision repair: A mechanism of trinucleotide repeat expansion
Expansion of trinucleotide repeat (TNR) sequences in human DNA is considered to be a key factor in the pathogenesis of more than 40 neurodegenerative diseases. TNR expansion occurs during DNA replication and also, as suggested by recent studies, during the repair of DNA lesions produced by oxidative...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323758/ https://ncbi.nlm.nih.gov/pubmed/22285516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.12.002 |
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