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The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule
Although the major histocompatibility complex class I (MHC-I) molecules typically bind short peptide (p) fragments (8–10 amino acids in length), longer, “bulged” peptides are often be presented by MHC-I. Such bulged pMHC-I complexes represent challenges for T-cell receptor (TCR) ligation, although t...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320977/ https://ncbi.nlm.nih.gov/pubmed/22343629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344689 |
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