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A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

Mutations within T cell epitopes represent a common mechanism of viral escape from the host protective immune response. The diverse T cell repertoire and the extensive human leukocyte antigen (HLA) polymorphism across populations is the evolutionary response to viral mutation. However, the molecular...

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Detalhes bibliográficos
Main Authors: Liu, Yu Chih, Chen, Zhenjun, Neller, Michelle A., Miles, John J., Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie, Gras, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059114/
https://ncbi.nlm.nih.gov/pubmed/24759101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563502
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