Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

Human leukocyte antigen (HLA) gene polymorphism plays a critical role in protective immunity, disease susceptibility, autoimmunity, and drug hypersensitivity, yet the basis of how HLA polymorphism influences T cell receptor (TCR) recognition is unclear. We examined how a natural micropolymorphism in...

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Bibliografiset tiedot
Päätekijät: Archbold, Julia K., Macdonald, Whitney A., Gras, Stephanie, Ely, Lauren K., Miles, John J., Bell, Melissa J., Brennan, Rebekah M., Beddoe, Travis, Wilce, Matthew C.J., Clements, Craig S., Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2009
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626662/
https://ncbi.nlm.nih.gov/pubmed/19139173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082136
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