Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

Human leukocyte antigen (HLA) gene polymorphism plays a critical role in protective immunity, disease susceptibility, autoimmunity, and drug hypersensitivity, yet the basis of how HLA polymorphism influences T cell receptor (TCR) recognition is unclear. We examined how a natural micropolymorphism in...

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Bibliografische gegevens
Hoofdauteurs: Archbold, Julia K., Macdonald, Whitney A., Gras, Stephanie, Ely, Lauren K., Miles, John J., Bell, Melissa J., Brennan, Rebekah M., Beddoe, Travis, Wilce, Matthew C.J., Clements, Craig S., Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2009
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626662/
https://ncbi.nlm.nih.gov/pubmed/19139173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082136
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