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Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
αβ T cell receptors (TCRs) are genetically restricted to corecognize peptide antigens bound to self-major histocompatibility complex (pMHC) molecules; however, the basis for this MHC specificity remains unclear. Despite the current dogma, evaluation of the TCR–pMHC-I structural database shows that t...
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890827/ https://ncbi.nlm.nih.gov/pubmed/20483993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004926107 |
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