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Talin Contains A C-Terminal Calpain2 Cleavage Site Important In Focal Adhesion Dynamics
Talin is a large (∼2540 residues) dimeric adaptor protein that associates with the integrin family of cell adhesion molecules in cell-extracellular matrix junctions (focal adhesions; FAs), where it both activates integrins and couples them to the actin cytoskeleton. Calpain2-mediated cleavage of tal...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319578/ https://ncbi.nlm.nih.gov/pubmed/22496808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034461 |
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