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Design and Synthesis of Cannabinoid Receptor 1 Antagonists for Peripheral Selectivity
Antagonists of cannabinoid receptor 1 (CB1) have potential for the treatment of several diseases such as obesity, liver disease and diabetes. Recently, development of several CB1 antagonists was halted due to adverse central nervous system (CNS) related side effects observed with rimonabant, the fir...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319116/ https://ncbi.nlm.nih.gov/pubmed/22372835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201731z |
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