Structure, Stability, and Aggregation of β-2 Microglobulin Mutants: Insights from a Fourier Transform Infrared Study in Solution and in the Crystalline State

β-2 microglobulin (β2m) is an amyloidogenic protein involved in dialysis-related amyloidosis. We report here the study of the structural properties of the protein in solution and in the form of single crystals by Fourier transform infrared (FTIR) spectroscopy and microspectroscopy. The investigation...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ami, Diletta, Ricagno, Stefano, Bolognesi, Martino, Bellotti, Vittorio, Doglia, Silvia Maria, Natalello, Antonino
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Spectroscopy, Imaging, and Other Techniques
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318121/
https://ncbi.nlm.nih.gov/pubmed/22500768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.045
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge